Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119258 | 1.00 | HTR1A (1.00) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9441254 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9120284 | 0.99 | HTR1A (0.97) | HTR1ADRD2 | |
| SCHEMBL9272448 | 0.92 | HTR1A (0.86) | HTR1ADRD2 | |
| SCHEMBL9272444 | 0.92 | HTR1A (0.86) | HTR1ADRD2 | |
| SCHEMBL7883659 | 0.88 | HTR1A (0.79) | HTR1ADRD2 | |
| SCHEMBL7874795 | 0.88 | HTR1A (0.79) | HTR1ADRD2 | |
| SCHEMBL7875480 | 0.88 | HTR1A (0.79) | HTR1ADRD2 | |
| SCHEMBL7876193 | 0.88 | HTR1A (0.79) | HTR1ADRD2 | |
| Bromide SCHEMBL11896070 | 0.87 | HTR1A (0.77) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548664-B1 | 2,3,3a-5,9b-hexahydro-1H-benzo(e)indole derivatives | HOFFMANN LA ROCHE (CH) | 1995-05-31 | — | — | EP | disclosed |
| EP-0548664-A1 | 2,3,3a-5,9b-hexahydro-1H-benzo(e)indole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-30 | — | — | EP | disclosed |