Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 4/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107971 | 0.90 | GHSR (0.46) | NPSR1ALDH1A1HPGDGAAGHSR | |
| SCHEMBL9107966 | 0.90 | GHSR (0.46) | NPSR1ALDH1A1HPGDGAAGHSR | |
| SCHEMBL9120215 | 0.88 | GHSR (0.41) | NPSR1ALDH1A1HPGDGHSRAGTR1 | |
| SCHEMBL9108460 | 0.87 | GHSR (0.46) | GHSRAGTR1XIAP | |
| SCHEMBL9037178 | 0.87 | GHSR (0.46) | GHSRAGTR1XIAP | |
| SCHEMBL9119353 | 0.84 | GHSR (0.38) | GHSRAGTR1XIAP | |
| SCHEMBL9108441 | 0.83 | GHSR (0.51) | GHSRAGTR1XIAP | |
| SCHEMBL9105393 | 0.82 | GHSR (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9106020 | 0.82 | GHSR (0.58) | GHSRAGTR1XIAP | |
| SCHEMBL9104298 | 0.81 | GHSR (0.59) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003290-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |