SCHEMBL9119562

SCHEMBL9119562

C[CH]Oc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.70
HPGD P15428 4/20 0.70
MAPK1 P28482 3/20 0.70
CYP1A2 P05177 2/20 0.70
PGR P06401 2/20 0.70
SLC6A2 P23975 2/20 0.70
CYP2C19 P33261 2/20 0.70
HTT P42858 2/20 0.70
ALDH1A1 P00352 2/20 0.70
CYP2D6 P10635 1/20 0.70
PDE4A P27815 1/20 0.70
HRH1 P35367 1/20 0.70
SLC6A3 Q01959 1/20 0.70
PDE4D Q08499 1/20 0.70
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
USP2 O75604 1/20 0.61
GAA P10253 1/20 0.61
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064519 0.88 LMNA (0.67) LMNAHPGDMAPK1CYP1A2PGR
SCHEMBL3118907 0.85 LMNA (0.66) LMNAHPGDMAPK1CYP1A2PGR
SCHEMBL14429578 0.85 LMNA (0.66) LMNAHPGDMAPK1CYP1A2PGR
SCHEMBL27881612 0.84 HPGD (0.65) LMNAHPGDMAPK1CYP1A2PGR
Oxybenzone SCHEMBL6674080 0.83 HPGD (1.00) LMNAHPGDMAPK1CYP1A2PGR
Oxybenzone SCHEMBL15551 0.83 HPGD (1.00) LMNAHPGDMAPK1CYP1A2PGR
Oxybenzone SCHEMBL419361 0.83 HPGD (1.00) LMNAHPGDMAPK1CYP1A2PGR
Oxybenzone SCHEMBL5161586 0.83 HPGD (1.00) LMNAHPGDMAPK1CYP1A2PGR
Oxybenzone SCHEMBL29355332 0.83 HPGD (1.00) LMNAHPGDMAPK1CYP1A2PGR
SCHEMBL15548086 0.82 LMNA (0.67) LMNAHPGDMAPK1CYP1A2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US claimed
US-5241067-A Imparting heat, light and oxidation resistance to polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-31 US claimed
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US disclosed
US-5408008-A Piperidinyl phthalimide hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-04-18 US disclosed
US-5241067-A Imparting heat, light and oxidation resistance to polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-31 US disclosed
EP-0355043-A1 Multi-component coating composition comprising an anhydride containing polymer, a glycidyl component and a phosphonium catalyst E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-02-21 EP disclosed
EP-0224915-A2 Amine vapor curable coating composition of an acrylic polymer and a polyisocyanate E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-10 EP disclosed
EP-0067989-A1 THERMOSETTING ACRYLIC ENAMEL STABILIZED AGAINST WEATHERING BY ADDITION OF ULTRAVIOLET LIGHT STABILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed
WO-1982002397-A1 THERMOSETTING ACRYLIC ENAMEL STABILIZED AGAINST WEATHERING BY ADDITION OF ULTRAVIOLET LIGHT STABILIZER DU PONT (US) 1982-07-22 WO disclosed