Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122689 | 0.96 | CYP19A1 (0.56) | CYP19A1CYP3A4CYP2D6MAPK1MTOR | |
| SCHEMBL9728051 | 0.91 | CYP19A1 (0.51) | CYP19A1 | |
| SCHEMBL9728037 | 0.87 | CYP19A1 (0.55) | CYP19A1 | |
| SCHEMBL9119383 | 0.86 | CYP19A1 (0.43) | CYP19A1 | |
| SCHEMBL9120192 | 0.85 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL9120327 | 0.85 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL9122156 | 0.81 | HRH1 (0.42) | CYP19A1 | |
| SCHEMBL9119587 | 0.81 | CYP19A1 (0.49) | CYP19A1MAPK1 | |
| SCHEMBL9120034 | 0.81 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL9092229 | 0.81 | CYP19A1 (0.56) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390558-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-09-07 | — | — | EP | claimed |
| EP-0390558-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1990-10-03 | — | — | EP | claimed |
| US-5439928-A | Enzyme inhibitors as antitumor agents for breast cancer | ORION-YHTYMA OY (FI) | 1995-08-08 | — | — | US | disclosed |
| EP-0390558-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-09-07 | — | — | EP | disclosed |
| EP-0390558-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1990-10-03 | — | — | EP | disclosed |