Known targets — ChEMBL curated mechanism
CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8
The experimentally established mechanism targets of Phloroglucinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA7 | P43166 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orcinol SCHEMBL998779 | 0.87 | ALDH1A1 (0.71) | BACE1LCKTDP1CA12CA2 | |
| Phloroglucinol SCHEMBL22032286 | 0.82 | BACE1 (0.80) | BACE1LCKTDP1CA12CA2 | |
| Phloroglucinol SCHEMBL30542958 | 0.82 | — | — | |
| Phloroglucinol SCHEMBL26311 | 0.82 | — | — | |
| Phloroglucinol SCHEMBL2889628 | 0.82 | BACE1 (1.00) | BACE1LCKTDP1CA12CA2 | |
| Resorcinol SCHEMBL352512 | 0.79 | ALDH1A1 (0.75) | LCKTDP1CA12CA2CA9 | |
| Flamenol SCHEMBL69428 | 0.79 | CYP3A4 (0.62) | BACE1TDP1CA2CA1CYP3A4 | |
| Flamenol SCHEMBL3190965 | 0.77 | CYP3A4 (0.59) | BACE1TDP1CA2CA1CYP3A4 | |
| Methoxymethane SCHEMBL11527276 | 0.77 | CYP3A4 (0.50) | BACE1LCKTDP1CA12CA2 | |
| Phloroglucinol SCHEMBL23346245 | 0.77 | BACE1 (0.89) | BACE1LCKTDP1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119595807-A | Method for measuring impurity content in phloroglucinol trimethyl ether | 康普药业股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119330813-A | Preparation method of phloroglucinol trimethyl ether | 山西阳和药业有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-111888288-A | Preparation method of Chinese herbal medicine damp-clearing shampoo | 百色学院 | 2020-11-06 | — | — | CN | claimed |
| CN-105461525-A | Preparation of 1,3,5-tri-formyl trihydroxybenzene and reuse method of trifluoroacetic acid in preparation process | UNIV SOUTH CHINA TECH | 2016-04-06 | — | — | CN | claimed |
| CN-103755529-B | A kind of method preparing pyrogallol and Phloroglucinol monomethyl ether | SHOUGUANG FUKANG PHARMACEUTICAL CO., LTD. (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-105348492-A | Low temperature super fast-drying cardanol modified amine epoxy curing agent and preparation method thereof | SHANGHAI STEPOVRECHEM CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-105217605-A | Preparation method of patterned graphene | HEFEI GUOXUAN HIGH TECH POWER ENERGY CO LTD | 2016-01-06 | — | — | CN | claimed |
| CN-105061223-A | High-temperature benzenetriamine antioxidants for lubricating oil and preparation method of high-temperature benzenetriamine antioxidants | UNIV HENAN | 2015-11-18 | — | — | CN | claimed |
| CN-103708438-B | A kind of fluorine-containing meso-porous carbon material and preparation method thereof | TIANJIN UNIVERSITY (CN) | 2015-10-14 | — | — | CN | claimed |
| CN-104876209-A | Preparation method of graphene film | HEFEI GUOXUAN HIGH TECH POWER ENERGY CO LTD | 2015-09-02 | — | — | CN | claimed |
| CN-101774581-B | Method for preparing tungsten carbide/carbon aerogel composite material by alternate microwave heating | UNIV SUN YAT SEN | 2012-07-11 | — | — | CN | claimed |
| CN-102559169-A | Arborization three-nucleus cyclometallation platinum coordination compound electro-phosphorescent material and application of electro-phosphorescent material in polymer electroluminescence white light emitting device | UNIV XIANGTAN | 2012-07-11 | — | — | CN | claimed |
| CN-102517615-A | Sn-Ag alloy electroplate liquid | GALVANIZING BRANCH OF ZHANGJIAGANG SCHUMACHER ELEVATOR INSTALLATION MAINTENANCE SERVICE CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-101927994-A | Method for preparing monodisperse nano hollow carbon sphere with controllable size and shape | UNIV DALIAN TECH | 2010-12-29 | — | — | CN | claimed |
| CN-101774581-A | Method for preparing tungsten carbide/carbon aerogel composite material by alternate microwave heating | UNIV SUN YAT SEN | 2010-07-14 | — | — | CN | claimed |
| CN-100497351-C | Multiple functional group silicide preparation method | HANGZHOU TEACHERS COLLEGE (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-101235131-A | Method for preparing benzoxazine intermediate containing propargyl ether and resin thereof | UNIV SHANDONG (CN) | 2008-08-06 | — | — | CN | claimed |
| US-4429138-A | MULTISTEP, FROM PHLOROGLUCINOL | GOUPIL JEAN JACQUES (FR) | 1984-01-31 | — | — | US | claimed |
| EP-0001733-B1 | 5-METHOXY-PSORALENE AS A NEW MEDICAMENT AND PROCESS FOR THE SYNTHESIS | Goupil, Jean-Jacques (FR) | 1982-06-23 | — | — | EP | claimed |
| US-4112003-A | Process for preparing polyphenols | GIVAUDAN CORPORATION (US) | 1978-09-05 | — | — | US | claimed |