Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.89 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.89 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121929 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9122607 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9120828 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9119895 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9122551 | 0.94 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9119706 | 0.93 | LTB4R (0.98) | LTB4RLTB4R2 | |
| SCHEMBL9119715 | 0.93 | LTB4R (0.98) | LTB4RLTB4R2 | |
| SCHEMBL9120851 | 0.93 | LTB4R (0.95) | LTB4RLTB4R2 | |
| SCHEMBL9122293 | 0.92 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL9121228 | 0.92 | LTB4R (0.90) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531823-A1 | Bicyclic carboxylic acid derivatives as anti-inflammatory agents | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-17 | — | — | EP | claimed |
| US-5434186-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1995-07-18 | — | — | US | disclosed |
| US-5273999-A | A 4-keto-boroalkyleneoxychroman or 2,3-dihydrobenzofuran derivative | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0531823-A1 | Bicyclic carboxylic acid derivatives as anti-inflammatory agents | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-17 | — | — | EP | disclosed |