Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121982 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9125350 | 0.86 | GRM8 (0.43) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9125343 | 0.86 | GRM8 (0.43) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9121452 | 0.85 | USP2 (0.44) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9120958 | 0.85 | USP2 (0.41) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9120952 | 0.85 | USP2 (0.41) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9122929 | 0.85 | CYP1A2 (0.52) | ALDH1A1ALOX15KMT2AHSD17B10CYP3A4 | |
| SCHEMBL9121716 | 0.85 | PTPRC (0.44) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9121717 | 0.85 | PTPRC (0.44) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E | |
| SCHEMBL9122537 | 0.85 | USP2 (0.41) | ALDH1A1ALOX15KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | claimed |
| US-5395827-A | Analgesic, anticonvulsant, antiepileptic and anxiolytic agents | GUILFORD PHARMACEUTICALS INC. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |