Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350454 | 0.74 | CYP19A1 (0.59) | CYP19A1 | |
| SCHEMBL9783848 | 0.74 | CYP19A1 (0.60) | CYP19A1KCNH2HRH4HRH3 | |
| SCHEMBL6546797 | 0.73 | CYP19A1 (0.56) | CYP19A1 | |
| SCHEMBL9783740 | 0.72 | CYP19A1 (0.68) | CYP19A1KCNH2HRH4HRH3 | |
| SCHEMBL9121789 | 0.71 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL9783364 | 0.70 | CYP19A1 (0.58) | CYP19A1KCNH2HRH4HRH3 | |
| SCHEMBL9123737 | 0.70 | CYP11B1 (0.55) | CYP19A1 | |
| SCHEMBL9120038 | 0.70 | CYP11B1 (0.55) | CYP19A1 | |
| SCHEMBL9783539 | 0.69 | CYP19A1 (0.60) | CYP19A1KCNH2HRH4HRH3 | |
| SCHEMBL6546957 | 0.69 | CYP19A1 (0.51) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439928-A | Enzyme inhibitors as antitumor agents for breast cancer | ORION-YHTYMA OY (FI) | 1995-08-08 | — | — | US | disclosed |
| EP-0390558-B1 | Aromatase inhibiting 4(5)-imidazoles | ORION YHTYMAE OY (FI) | 1994-09-07 | — | — | EP | disclosed |
| EP-0390558-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1990-10-03 | — | — | EP | disclosed |