SCHEMBL912271

SCHEMBL912271

CCN(C)/C=N\c1cc(C)c(Oc2ccc(Cl)c(C(C)C)c2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.35
SLC6A4 P31645 9/20 0.35
KCNH2 Q12809 8/20 0.35
THRB P10828 1/20 0.33
RORC P51449 1/20 0.33
SLC6A2 P23975 1/20 0.31
SLC6A3 Q01959 1/20 0.31
G6PD P11413 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL912272 1.00 HTR2A (0.35) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL22176951 0.91 RORC (0.38) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL3309490 0.90 HTR2A (0.33) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL912742 0.90 HTR2A (0.33) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL912743 0.90 HTR2A (0.33) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL913233 0.88 AR (0.35) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL913232 0.88 AR (0.35) HTR2ASLC6A4KCNH2THRBRORC
SCHEMBL3304313 0.88 HTR2A (0.44) HTR2ASLC6A4KCNH2SLC6A2SLC6A3
SCHEMBL3304309 0.88 HTR2A (0.44) HTR2ASLC6A4KCNH2SLC6A2SLC6A3
SCHEMBL3308670 0.85 HTR2A (0.34) HTR2ASLC6A4KCNH2SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110003689-A1 USE OF POLYMERIC GUANIDINE DERIVATIVES FOR THE CONTROL OF UNWANTED MICROORGANISMS IN CROP PROTECTION AKA TECHNOLOGY GMBH (AT) 2011-01-06 US claimed
EP-2230915-A2 USE OF POLYMER GUANIDINE DERIVATIVES FOR COMBATING UNDESIRED MICROORGANISMS IN PEST MANAGEMENT Aka Technology Gmbh (AT) 2010-09-29 EP claimed
WO-2009077098-A2 USE OF POLYMER GUANIDINE DERIVATIVES FOR COMBATING UNDESIRED MICROORGANISMS IN PEST MANAGEMENT BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-06-25 WO claimed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
US-20110003689-A1 USE OF POLYMERIC GUANIDINE DERIVATIVES FOR THE CONTROL OF UNWANTED MICROORGANISMS IN CROP PROTECTION AKA TECHNOLOGY GMBH (AT) 2011-01-06 US disclosed
EP-2071954-A1 Use of polymeric guanidine derivatives for combating unwanted micro-organisms in the protection of plants Bayer CropScience AG (DE) 2009-06-24 EP disclosed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003689-A1 USE OF POLYMERIC GUANIDINE DERIVATIVES FOR THE CONTROL OF UNWANTED MICROORGANISMS IN CROP PROTECTION GDA, GMPS, GANC HTR2A 2990/4885SLC6A4 3186/4885KCNH2 2368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.