Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122826 | 1.00 | TSHR (0.44) | TSHRALDH1A1THRBATMHCAR2 | |
| SCHEMBL9120592 | 0.86 | ATM (0.51) | TSHRALDH1A1THRBATMHCAR2 | |
| SCHEMBL9120573 | 0.86 | ATM (0.51) | TSHRALDH1A1THRBATMHCAR2 | |
| SCHEMBL3085589 | 0.84 | HCAR2 (0.53) | TSHRALDH1A1ATMHCAR2MAPT | |
| SCHEMBL3962443 | 0.84 | HCAR2 (0.50) | TSHRALDH1A1ATMHCAR2HSD17B10 | |
| SCHEMBL9122990 | 0.84 | HCAR2 (0.50) | TSHRALDH1A1ATMHCAR2HSD17B10 | |
| SCHEMBL9124169 | 0.83 | ATM (0.37) | TSHRALDH1A1ATMHCAR2TP53 | |
| SCHEMBL9124143 | 0.83 | ATM (0.37) | TSHRALDH1A1ATMHCAR2TP53 | |
| SCHEMBL2897724 | 0.80 | ALDH1A1 (0.60) | TSHRALDH1A1THRBATMHCAR2 | |
| SCHEMBL2898088 | 0.80 | ALDH1A1 (0.60) | TSHRALDH1A1THRBATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347044-A | Trans-beta-isocyanatoacrylate esters, their preparation, and polymers made therefrom | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1994-09-13 | — | — | US | claimed |
| US-5401819-A | Trans-beta-isocyanatoacrylate esters, their preparation, and polymers made therefrom | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1995-03-28 | — | — | US | disclosed |
| US-5347044-A | Trans-beta-isocyanatoacrylate esters, their preparation, and polymers made therefrom | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1994-09-13 | — | — | US | disclosed |