Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417085 | 0.87 | LMNA (0.60) | MAPTTSHRPLA2G4BALDH1A1LMNA | |
| SCHEMBL9574365 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL9417076 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL8496739 | 0.86 | MAPT (0.55) | MAPTTSHRGAAPLA2G4BLMNA | |
| SCHEMBL9416946 | 0.86 | MAPT (0.55) | MAPTTSHRGAAPLA2G4BLMNA | |
| SCHEMBL9574428 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL8457408 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL9574345 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL8457405 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 | |
| SCHEMBL9574307 | 0.86 | PLA2G4B (0.65) | TSHRPLA2G4BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428720-B1 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE | MERCK PATENT GMBH (DE) | 1995-03-22 | — | — | EP | disclosed |
| US-5393459-A | Optically active compounds, and a liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-28 | — | — | US | disclosed |
| EP-0428720-A1 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990013611-A2 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-15 | — | — | WO | disclosed |