Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125254 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL9124057 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAGAATDP1 | |
| SCHEMBL9124111 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL9124844 | 0.80 | MAPT (0.37) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL9120870 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL9125001 | 0.77 | MAPT (0.37) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL3752019 | 0.74 | MAPT (0.40) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL502077 | 0.74 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11497906 | 0.73 | TDP1 (0.47) | ALDH1A1MAPTMEN1POLBKMT2A | |
| SCHEMBL3666271 | 0.72 | MAPT (0.38) | ALDH1A1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397781-A | Pyrimidine derivatives | MOCHIDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0561175-A1 | Pyrimidine derivatives and pharmaceutical compostions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-22 | — | — | EP | disclosed |