Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122711 | 0.89 | ALDH1A1 (0.49) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9538080 | 0.88 | MAPK1 (0.59) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9122833 | 0.88 | ALDH1A1 (0.46) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9123615 | 0.88 | ALDH1A1 (0.47) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9120922 | 0.88 | ALDH1A1 (0.47) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9120586 | 0.88 | ALDH1A1 (0.47) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9122385 | 0.88 | ALDH1A1 (0.50) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL10770505 | 0.86 | ALDH1A1 (0.58) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9123818 | 0.85 | ALDH1A1 (0.46) | ALDH1A1RECQLMAPK1ATMMAPT | |
| SCHEMBL9122492 | 0.84 | ALDH1A1 (0.44) | ALDH1A1RECQLMAPK1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395827-A | Analgesic, anticonvulsant, antiepileptic and anxiolytic agents | GUILFORD PHARMACEUTICALS INC. (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1993005772-A1 | φ-[2-(PHOSPHONOALKYL)PHENYL]-2-AMINOALKANOIC ACIDS AS ANTAGONISTS OF EXCITATORY AMINO ACID RECEPTORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |