Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.87 |
| ▸ | CCKAR | P32238 | 12/20 | 0.87 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.76 |
| ▸ | TSPO | P30536 | 1/20 | 0.76 |
| ▸ | GLP1R | P43220 | 1/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.76 |
| ▸ | PDE4A | P27815 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | PDE5A | O76074 | 2/20 | 0.60 |
| ▸ | PDE1A | P54750 | 2/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.60 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.60 |
| ▸ | OXTR | P30559 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125285 | 0.93 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9125278 | 0.93 | CCKBR (1.00) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9122778 | 0.92 | CCKBR (0.81) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9122784 | 0.92 | CCKBR (0.81) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9122790 | 0.92 | CCKBR (0.81) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9124099 | 0.91 | CCKBR (0.80) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9124094 | 0.91 | CCKBR (0.80) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9124086 | 0.91 | CCKBR (0.80) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9459250 | 0.89 | CCKBR (0.82) | CCKBRCCKARADRB2TSPOGLP1R | |
| SCHEMBL9124657 | 0.89 | CCKBR (0.82) | CCKBRCCKARADRB2TSPOGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382664-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5264433-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4970207-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| EP-0349949-A2 | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |