Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506074 | 0.86 | TDP1 (0.53) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL5132603 | 0.84 | TDP1 (0.56) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL2346408 | 0.82 | MAPT (0.51) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL7153128 | 0.82 | TDP1 (0.51) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL28712215 | 0.82 | ATM (0.44) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL4211363 | 0.82 | TDP1 (0.50) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL829508 | 0.82 | TSHR (0.56) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL28363002 | 0.82 | TDP1 (0.54) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL28968200 | 0.82 | TDP1 (0.50) | TDP1ATMLMNAF2ALDH1A1 | |
| SCHEMBL4089336 | 0.82 | TDP1 (0.50) | TDP1ATMLMNAF2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961323-A | Degradable material suitable for low-temperature well and preparation method and application thereof | 上海浦景化工技术股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-111944290-A | Degradable material suitable for high-temperature well and product and application thereof | 上海浦景化工技术股份有限公司 | 2020-11-17 | — | — | CN | disclosed |
| US-5391664-A | Having hydroxyl groups at both terminals | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |