Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.30 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468276 | 0.81 | EPHX2 (0.39) | KDM4EALDH1A1LMNAMAPTPTK2B | |
| SCHEMBL5964167 | 0.78 | — | — | |
| SCHEMBL5963734 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPT | |
| SCHEMBL530103 | 0.74 | — | — | |
| SCHEMBL10942608 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL31309 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPT | |
| SCHEMBL5963570 | 0.73 | — | — | |
| SCHEMBL1177851 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL10978829 | 0.69 | — | — | |
| SCHEMBL7608770 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413627-A | Scrubbing with saturated or unsaturated heterocyclic nitrogen compound, amine, amide, urea, hydrazine, hydrazide, hydrazone functional groups | LINDE AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |