Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | VCP | P55072 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978641 | 0.90 | VCP (0.75) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL28972852 | 0.88 | MEN1 (0.60) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL30114976 | 0.88 | MEN1 (0.60) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL30114847 | 0.88 | VCP (0.68) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL5592874 | 0.88 | VCP (0.68) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL17348262 | 0.88 | HSP90AA1 (0.60) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL28574185 | 0.88 | HSP90AA1 (0.60) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL10625119 | 0.85 | VCP (0.81) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL27763784 | 0.84 | MEN1 (0.56) | HSP90AA1NPSR1ALDH1A1MAPTHTT | |
| SCHEMBL30114938 | 0.82 | VCP (0.60) | HSP90AA1NPSR1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449740-A | Resin systems derived from insitu-generated bisdienes from bis-benzocyclobutene compounds | THE UNIVERSITY OF DAYTON (US) | 1995-09-12 | — | — | US | disclosed |