Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125716 | 0.97 | MCHR1 (0.39) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9126017 | 0.97 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9125250 | 0.97 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9127067 | 0.97 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9127821 | 0.94 | MCHR1 (0.38) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9127454 | 0.93 | TLR4 (0.42) | TLR4SSTR2SSTR3SSTR5SELP | |
| SCHEMBL9124536 | 0.93 | TLR4 (0.42) | TLR4SSTR2SSTR3SSTR5SELP | |
| SCHEMBL9126453 | 0.92 | MEN1 (0.40) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9125721 | 0.92 | TLR4 (0.43) | TLR4MCHR1SSTR2SSTR3SSTR5 | |
| SCHEMBL9125712 | 0.92 | TLR4 (0.43) | TLR4MCHR1SSTR2SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |