Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.66 |
| ▸ | NAAA | Q02083 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123172 | 1.00 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL8811889 | 1.00 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL6682080 | 1.00 | HDAC1 (0.66) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL19287095 | 0.98 | HDAC1 (0.63) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL8891043 | 0.94 | HDAC1 (0.59) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL1193202 | 0.93 | NPC1 (0.62) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9188890 | 0.88 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL7460068 | 0.88 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL20734829 | 0.88 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL9492235 | 0.88 | HDAC1 (0.82) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160138077-A1 | MONITORING AND ASSESSING DEACETYLASE ENZYME ACTIVITY | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-19 | — | — | US | disclosed |
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160138077-A1 | MONITORING AND ASSESSING DEACETYLASE ENZYME ACTIVITY | HDAC1, HDAC2, HDAC3 | HDAC1 1/4885HDAC2 2/4885HDAC8 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.