Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126391 | 0.86 | TNIK (0.49) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9126080 | 0.85 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9125517 | 0.85 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9126182 | 0.85 | GSK3B (0.39) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9124310 | 0.83 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7197815 | 0.83 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9127603 | 0.81 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL9125166 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20302856 | 0.80 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8391733 | 0.80 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |