Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374722 | 1.00 | NR4A2 (0.54) | NR4A2ABL1SLC6A4SLC6A3RXFP1 | |
| SCHEMBL3571702 | 0.87 | NR4A2 (0.54) | NR4A2ABL1SLC6A4SLC6A3RXFP1 | |
| SCHEMBL29792644 | 0.87 | NR4A2 (0.54) | NR4A2ABL1SLC6A4SLC6A3RXFP1 | |
| SCHEMBL4961105 | 0.87 | PTPN1 (0.45) | NR4A2KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL19733167 | 0.83 | ALDH1A1 (0.56) | SLC6A4SLC6A3KDM4ENPSR1ALDH1A1 | |
| SCHEMBL13576763 | 0.82 | KDM4E (0.60) | NR4A2ABL1SLC6A4SLC6A3KDM4E | |
| SCHEMBL30571222 | 0.82 | CA12 (0.54) | SLC6A4SLC6A3KDM4ENPSR1ALDH1A1 | |
| SCHEMBL69179 | 0.82 | LCK (0.58) | SLC6A4SLC6A3KDM4ENPSR1ALDH1A1 | |
| SCHEMBL343944 | 0.82 | NR4A2 (0.53) | NR4A2SLC6A4SLC6A3KDM4ENPSR1 | |
| SCHEMBL30213808 | 0.82 | LCK (0.58) | SLC6A4SLC6A3KDM4ENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395849-A | Hybrid antitumor compounds containing a cyclic enediyne and a DNA-binder | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-03-07 | — | — | US | disclosed |