Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087029 | 0.98 | KMT2A (0.58) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL8402203 | 0.90 | KMT2A (0.67) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL9419411 | 0.88 | KMT2A (0.69) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL1040708 | 0.84 | KMT2A (0.64) | KMT2AL3MBTL1LMNAMAPTHSD17B3 | |
| SCHEMBL7383618 | 0.83 | GSK3B (0.62) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL9352262 | 0.83 | KMT2A (0.75) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL9352285 | 0.83 | KMT2A (0.75) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL7736066 | 0.83 | GSK3B (0.62) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL9352247 | 0.83 | KMT2A (0.75) | KMT2AL3MBTL1TDP1LMNAMAPT | |
| SCHEMBL19047793 | 0.83 | HSD17B3 (0.73) | KMT2AL3MBTL1TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |