Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.32 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.32 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.32 |
| ▸ | PSMB3 | P49720 | 5/20 | 0.32 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.32 |
| ▸ | PSMA6 | P60900 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125703 | 1.00 | PSMB5 (0.41) | PSMB5ALDH1A1F2MMP1PSMB11 | |
| SCHEMBL11761746 | 0.83 | PSMB5 (0.42) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL1006669 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MMP1NFKB1MAPT | |
| SCHEMBL1006670 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MMP1NFKB1MAPT | |
| SCHEMBL10582214 | 0.81 | SLC7A5 (0.38) | PSMB5 | |
| SCHEMBL5662013 | 0.81 | PSMB5 (0.37) | PSMB5 | |
| SCHEMBL5662018 | 0.81 | PSMB5 (0.37) | PSMB5 | |
| SCHEMBL8186529 | 0.81 | KDM4E (0.36) | F2NFKB1MAPT | |
| SCHEMBL8186521 | 0.81 | KDM4E (0.36) | F2NFKB1MAPT | |
| SCHEMBL11136853 | 0.78 | PSMB5 (0.41) | PSMB5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432263-A | Process for producing peptides with side chains containing imidazolinylamino, tetrahydropyrimidinylamino, or alkylguanidinyl groups | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |