SCHEMBL9126106

SCHEMBL9126106

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ VIPR2 P41587 6/20 0.45
▸ VIPR1 P32241 4/20 0.45
▸ GLP1R P43220 3/20 0.43
▸ F2 P00734 2/20 0.43
▸ C5AR1 P21730 1/20 0.43
▸ NPY4R P50391 5/20 0.43
▸ NPY1R P25929 4/20 0.43
▸ NPY2R P49146 4/20 0.43
▸ NPY5R Q15761 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9126093 1.00 VIPR2 (0.45) VIPR2VIPR1GLP1RF2C5AR1
SCHEMBL14921120 0.93 VIPR2 (0.44) VIPR2VIPR1GLP1RC5AR1NPY4R
SCHEMBL9551332 0.93 C5AR1 (0.46) VIPR2VIPR1GLP1RC5AR1NPY4R
SCHEMBL31612227 0.92 VIPR2 (0.52) VIPR2VIPR1GLP1R
SCHEMBL30293824 0.92 GLP1R (0.40) VIPR2VIPR1GLP1RNPY4RNPY1R
SCHEMBL31643038 0.91 GLP1R (0.42) VIPR2VIPR1GLP1RF2C5AR1
SCHEMBL29767364 0.90 GLP1R (0.50) VIPR2VIPR1GLP1R
SCHEMBL31399748 0.90 NPY4R (0.45) VIPR2VIPR1C5AR1NPY4RNPY1R
SCHEMBL31568000 0.89 NPY4R (0.52) VIPR2VIPR1GLP1RNPY4RNPY1R
SCHEMBL31567997 0.89 NPY4R (0.52) VIPR2VIPR1GLP1RNPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5470569-A Genetic engineering CETUS ONCOLOGY CORPORATION (US) 1995-11-28 — — US disclosed
EP-0272779-B1 New forms of colony stimulating factor-1 CETUS ONCOLOGY CORP (US) 1994-05-18 — — EP disclosed
US-5104650-A Promoting production of interferon by monocytes; overcoming immunosuppression caused by drugs CETUS CORPORATION (US) 1992-04-14 — — US disclosed
US-4847201-A GENETIC ENGINEERING CETUS CORPORATION (US) 1989-07-11 — — US disclosed
EP-0272779-A2 New forms of colony stimulating factor-1 CETUS ONCOLOGY CORPORATION (US) 1988-06-29 — — EP disclosed
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