Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 6/20 | 0.44 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | GLP1R | P43220 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256967 | 0.95 | VIPR2 (0.46) | VIPR2VIPR1CCNA2CDK2CCNA1 | |
| SCHEMBL9126106 | 0.93 | VIPR2 (0.45) | VIPR2VIPR1C5AR1NPY4RNPY1R | |
| SCHEMBL9126093 | 0.93 | VIPR2 (0.45) | VIPR2VIPR1C5AR1NPY4RNPY1R | |
| SCHEMBL31643038 | 0.92 | GLP1R (0.42) | VIPR2VIPR1CCNA2CDK2CCNA1 | |
| SCHEMBL29767364 | 0.90 | GLP1R (0.50) | VIPR2VIPR1GLP1R | |
| SCHEMBL16212659 | 0.89 | C5AR1 (0.54) | C5AR1 | |
| SCHEMBL9444822 | 0.89 | NPY4R (0.46) | C5AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9444799 | 0.89 | NPY4R (0.46) | C5AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30423377 | 0.89 | NPY4R (0.46) | C5AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31188462 | 0.89 | NPY4R (0.46) | C5AR1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109806395-A | Medical usage | 瓦力雷克斯有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-104136082-B | medical use | 瓦力雷克斯有限公司 | 2019-03-08 | — | — | CN | disclosed |
| EP-2773427-A2 | MEDICAL USE | Valirx Plc. (GB) | 2014-09-10 | — | — | EP | disclosed |
| WO-2013064830-A2 | MEDICAL USE | VALIRX PLC (GB) | 2013-05-10 | — | — | WO | disclosed |