Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124717 | 1.00 | KLK7 (0.41) | KLK7KLK5BCHEACHETLR2 | |
| SCHEMBL9568247 | 1.00 | KLK7 (0.41) | KLK7KLK5BCHEACHETLR2 | |
| SCHEMBL9127055 | 0.96 | KLK7 (0.45) | KLK7KLK5TLR4 | |
| SCHEMBL9126191 | 0.96 | KLK7 (0.45) | KLK7KLK5TLR4 | |
| SCHEMBL9128727 | 0.94 | TLR2 (0.41) | KLK7KLK5BCHEACHETLR2 | |
| SCHEMBL9127439 | 0.94 | TLR2 (0.41) | KLK7KLK5BCHEACHETLR2 | |
| SCHEMBL9126017 | 0.94 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9127067 | 0.94 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9125250 | 0.94 | TLR4 (0.41) | TLR4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9124729 | 0.91 | TLR4 (0.39) | TLR4MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |