SCHEMBL9126706

SCHEMBL9126706

C=C[C@]1(O)CC[C@H]2[C@@H]3[C@H](C)CC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 3/20 0.74
CYP19A1 P11511 2/20 0.63
ALDH1A1 P00352 2/20 0.58
AR P10275 2/20 0.48
NR3C1 P04150 2/20 0.47
PGR P06401 2/20 0.47
ADRA1A P35348 2/20 0.47
HTR2B P41595 2/20 0.47
CYP3A4 P08684 6/20 0.47
LMNA P02545 3/20 0.46
NFKB1 P19838 1/20 0.46
HIF1A Q16665 1/20 0.46
ABCB11 O95342 1/20 0.46
ESR1 P03372 1/20 0.46
CHRM2 P08172 1/20 0.46
ABCB1 P08183 1/20 0.46
NR3C2 P08235 1/20 0.46
CYP2C19 P33261 1/20 0.46
OPRK1 P41145 1/20 0.46
ESR2 Q92731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9126713 1.00 SHBG (0.74) SHBGCYP19A1ALDH1A1ARNR3C1
Bolasterone SCHEMBL10904938 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
Bolasterone SCHEMBL11876760 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
Bolasterone SCHEMBL4945157 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
Bolasterone SCHEMBL145066 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
SCHEMBL8340651 0.85 SHBG (0.82) SHBGCYP19A1ALDH1A1ARNR3C1
Calusterone SCHEMBL4509 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
Bolasterone SCHEMBL5656551 0.85 SHBG (1.00) SHBGCYP19A1ALDH1A1ARNR3C1
SCHEMBL8340653 0.85 SHBG (0.82) SHBGCYP19A1ALDH1A1ARNR3C1
SCHEMBL5700143 0.81 SHBG (0.76) SHBGCYP19A1ALDH1A1ARNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403710-B1 Polymerizable composition FUJIFILM CORP (JP) 2015-06-10 EP disclosed
EP-0949540-B1 Method for producing lithographic printing plate suitable for laser scan exposure, and photopolymerizable composition FUJIFILM CORP (JP) 2012-05-02 EP disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
US-7618762-B2 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-7618762-B2 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-7569328-B2 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION (JP) 2009-08-04 US disclosed
US-7569328-B2 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION (JP) 2009-08-04 US disclosed
EP-1344783-B1 Process for producing polymer compounds by elimination reaction FUJIFILM CORP (JP) 2009-05-13 EP disclosed
US-7455954-B2 Lithographic printing plate precursor and polymerizable composition FUJIFILM CORPORATION (JP) 2008-11-25 US disclosed
US-20080044763-A1 Resin composition and thermo/photosensitive composition FUJIFILM CORPORATION 2008-02-21 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-7179582-B2 Radical polymerizable composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed
US-5389624-A Antiandrogenic [3,2-c]pyrazole and [3,2-d]triazole steroids SCHERING AKTIENGESELLSCHAFT (DE) 1995-02-14 US disclosed
US-5236912-A Treating prostate hyperplasia and carcinoma SCHERING AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
US-5217845-A 9-Arylacridine as photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-08 US disclosed
EP-0538312-A1 Anti-androgenic [3,2-d]triazole steroids SCHERING AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
WO-1992000992-A1 ANTI-ANDROGENIC [3,2-c]PYRAZOLE AND [3,2-d]TRIAZOLE STEROIDS SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1992-01-23 WO disclosed