Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 3/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019559 | 1.00 | BCHE (0.35) | BCHESMYD3GSRKMT2ADRD2 | |
| SCHEMBL9127652 | 0.86 | BCHE (0.35) | BCHESMYD3GSRKMT2ACASP6 | |
| SCHEMBL9499642 | 0.86 | SMYD3 (0.39) | BCHESMYD3GSRKMT2ACASP6 | |
| SCHEMBL9497748 | 0.86 | SMYD3 (0.39) | BCHESMYD3GSRKMT2ACASP6 | |
| SCHEMBL9795289 | 0.86 | SMYD3 (0.39) | BCHESMYD3GSRKMT2ACASP6 | |
| SCHEMBL9019572 | 0.82 | MAPT (0.38) | BCHESMYD3KMT2ACASP6HTT | |
| SCHEMBL9125829 | 0.82 | MAPT (0.38) | BCHESMYD3KMT2ACASP6HTT | |
| SCHEMBL9127502 | 0.81 | BCHE (0.33) | BCHEGSRKMT2A | |
| SCHEMBL6439317 | 0.80 | BCHE (0.38) | BCHEGSRKDM1AATM | |
| SCHEMBL6439306 | 0.80 | BCHE (0.38) | BCHEGSRKDM1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |