Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MELK | Q14680 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499642 | 1.00 | SMYD3 (0.39) | SMYD3BCHEXIAPGSRKMT2A | |
| SCHEMBL9497748 | 1.00 | SMYD3 (0.39) | SMYD3BCHEXIAPGSRKMT2A | |
| SCHEMBL9127243 | 0.86 | BCHE (0.35) | SMYD3BCHEGSRKMT2ALMNA | |
| SCHEMBL9019559 | 0.86 | BCHE (0.35) | SMYD3BCHEGSRKMT2ALMNA | |
| SCHEMBL9127652 | 0.85 | BCHE (0.35) | SMYD3BCHEGSRKMT2ALMNA | |
| SCHEMBL9128912 | 0.83 | LMNA (0.36) | SMYD3BCHEKMT2ALMNABLM | |
| SCHEMBL9019595 | 0.83 | LMNA (0.36) | SMYD3BCHEKMT2ALMNABLM | |
| SCHEMBL9131574 | 0.82 | ALDH1A1 (0.33) | SMYD3BCHE | |
| SCHEMBL9019572 | 0.81 | MAPT (0.38) | SMYD3BCHEKMT2ALMNACASP6 | |
| SCHEMBL9125829 | 0.81 | MAPT (0.38) | SMYD3BCHEKMT2ALMNACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |