Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127322 | 1.00 | SHBG (0.53) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL11522845 | 0.85 | CYP19A1 (0.51) | SHBGALDH1A1CYP19A1NR3C1PGR | |
| SCHEMBL11522842 | 0.85 | CYP19A1 (0.51) | SHBGALDH1A1CYP19A1NR3C1PGR | |
| SCHEMBL9124485 | 0.79 | SHBG (0.41) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9124492 | 0.79 | SHBG (0.41) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9125973 | 0.76 | SHBG (0.63) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9125965 | 0.76 | SHBG (0.63) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9541910 | 0.75 | CYP19A1 (0.40) | SHBGALDH1A1CYP19A1NR3C1PGR | |
| SCHEMBL9541172 | 0.75 | CYP19A1 (0.40) | SHBGALDH1A1CYP19A1NR3C1PGR | |
| SCHEMBL9541167 | 0.75 | CYP19A1 (0.40) | SHBGALDH1A1CYP19A1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389624-A | Antiandrogenic [3,2-c]pyrazole and [3,2-d]triazole steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-02-14 | — | — | US | disclosed |
| US-5236912-A | Treating prostate hyperplasia and carcinoma | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |