Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | PPIF | P30405 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125551 | 0.91 | PPIA (0.53) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9125540 | 0.88 | PPIA (0.50) | PPIAALDH1A1CACNA1BAPBA1PPIF | |
| SCHEMBL9126812 | 0.88 | PPIA (0.52) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9124294 | 0.86 | PPIA (0.50) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9124740 | 0.84 | PPIA (0.55) | PPIAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9125751 | 0.84 | PPIA (0.54) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9126357 | 0.83 | PPIA (0.51) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9126321 | 0.83 | SGMS2 (0.50) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9126145 | 0.81 | PPIA (0.75) | PPIAALDH1A1PPIFMEN1KMT2A | |
| SCHEMBL9125562 | 0.80 | PPIA (0.46) | PPIAALDH1A1MEN1KMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |