Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 19/20 | 0.62 |
| ▸ | PPIF | P30405 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122625 | 0.94 | PPIA (0.56) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9122353 | 0.93 | PPIA (0.55) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9126271 | 0.91 | PPIA (0.53) | PPIAPPIFGRM5 | |
| Hydrochloric Acid SCHEMBL9125189 | 0.91 | PPIA (0.53) | PPIAPPIFGRM5 | |
| Hydrochloric Acid SCHEMBL9123728 | 0.86 | PPIA (0.48) | PPIAPPIF | |
| SCHEMBL9128491 | 0.86 | PPIA (0.48) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9125854 | 0.85 | PPIA (0.47) | PPIAGRM5 | |
| Hydrochloric Acid SCHEMBL9125163 | 0.85 | PPIA (0.54) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9124719 | 0.85 | PPIA (0.54) | PPIAPPIFGRM5 | |
| Hydrochloric Acid SCHEMBL9126773 | 0.85 | PPIA (0.48) | PPIAPPIFGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |
| EP-0625143-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015055-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |