Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 18/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPIF | P30405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128285 | 0.86 | PPIA (0.62) | PPIAPPIF | |
| SCHEMBL9357673 | 0.86 | PPIA (0.54) | PPIAALDH1A1PPIF | |
| Hydrochloric Acid SCHEMBL9125163 | 0.85 | PPIA (0.54) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9125854 | 0.85 | PPIA (0.47) | PPIA | |
| Hydrochloric Acid SCHEMBL9126899 | 0.85 | PPIA (0.48) | PPIAALDH1A1PPIF | |
| Hydrochloric Acid SCHEMBL9125056 | 0.82 | PPIA (0.48) | PPIAPPIF | |
| SCHEMBL9122625 | 0.81 | PPIA (0.56) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9122353 | 0.80 | PPIA (0.55) | PPIAPPIF | |
| Hydrochloric Acid SCHEMBL9124744 | 0.79 | PPIA (0.50) | PPIAALDH1A1PPIF | |
| Hydrochloric Acid SCHEMBL9124025 | 0.79 | PPIA (0.50) | PPIAPPIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |
| EP-0625143-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015055-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |