Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 4/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66310 | 0.92 | NT5E (0.74) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL564558 | 0.92 | NT5E (0.74) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL11502500 | 0.92 | NT5E (0.74) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL29429654 | 0.92 | NT5E (0.74) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL15221761 | 0.90 | NT5E (0.62) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL9805944 | 0.90 | NT5E (0.71) | NT5EPTPN1CASP6NSD2DUSP3 | |
| Water SCHEMBL11045842 | 0.90 | NT5E (0.71) | NT5EPTPN1CASP6NSD2DUSP3 | |
| Sulfuric Acid SCHEMBL9775004 | 0.90 | NT5E (0.71) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL564556 | 0.90 | NT5E (0.71) | NT5EPTPN1CASP6NSD2DUSP3 | |
| SCHEMBL9129766 | 0.86 | NT5E (0.67) | NT5EPTPN1CASP6NSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441983-A | Herpes simplex virus, human immunodeficiency virus | GENELABS INCORPORATED (US) | 1995-08-15 | — | — | US | disclosed |
| US-5409959-A | Administering sulfonate-substituted calixarene compound to inhibit thrombus formation | GENELABS INCORPORATED (US) | 1995-04-25 | — | — | US | disclosed |
| US-5312837-A | Method of treating viral infections with aryl macrocyclic compounds | GENELABS TECHNOLOGIES, INC. (US) | 1994-05-17 | — | — | US | disclosed |
| WO-1994003165-A1 | ANTITHROMBOTIC TREATMENT WITH CALIX(N)ARENE COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| WO-1994003164-A1 | INHIBITION AND TREATMENT OF INFECTION BY ENVELOPED VIRUS WITH CALIX(N) ARENE COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0569479-A1 | LONG-TERM DELIVERY DEVICE INCLUDING HYDROPHOBIC LOADING DOSE | GENELABS TECHNOLOGIES, INC. (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569533-A1 | ARYL MACROCYCLIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012709-A1 | ARYL MACROCYCLIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992012708-A1 | ANTI-COAGULANT PROPERTIES OF MACROCYCLIC COMPOUNDS AND METHOD OF TREATMENT | GENELABS TECHNOLOGIES, INC. (US) | 1992-08-06 | — | — | WO | disclosed |