Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.69 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.43 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502500 | 0.98 | NT5E (0.74) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL66310 | 0.98 | NT5E (0.74) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL564558 | 0.98 | NT5E (0.74) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL29429654 | 0.98 | NT5E (0.74) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL9805944 | 0.95 | NT5E (0.71) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL564556 | 0.95 | NT5E (0.71) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| Water SCHEMBL11045842 | 0.95 | NT5E (0.71) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL9129766 | 0.91 | NT5E (0.67) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| Methanesulfonamide SCHEMBL9128458 | 0.90 | NT5E (0.70) | NT5EPTPN1PRMT1APEX1ALDH1A1 | |
| SCHEMBL15221761 | 0.88 | NT5E (0.62) | NT5EPTPN1PRMT1APEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101732607-A | Method for detecting quality of huaqi Chinese medicinal preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-06-16 | — | — | CN | claimed |
| CN-101637567-A | Rhizoma ligustici wallichii quality control method in Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-02-03 | — | — | CN | claimed |
| CN-101637566-A | Salvia miltiorrhiza quality control method in Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-02-03 | — | — | CN | claimed |
| CN-101596274-A | The method of quality control of Fructus Schisandrae Chinensis in the YIXINSHU Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101036748-A | Quality control method of the Yixinshu Chinese traditional medicine for supplementing qi and for promoting blood circulation by removing blood stasis | GUIZHOU XINBANG PHARMACEUTICAL (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-1621836-A | Quality controlling method for pulse restoring injection | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2005-06-01 | — | — | CN | claimed |
| JP-3246209-A | — | — | None | — | — | JP | disclosed |
| CN-101732607-B | Method for detecting quality of huaqi Chinese medicinal preparation | GUIZHOU XINBANG PHARMACEUTICAL CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-101036748-B | Detection method of the Yixinshu Chinese traditional medicine for supplementing qi and for promoting blood circulation by removing blood stasis | GUIZHOU XINBANG PHARMACEUTICAL CO LTD | 2011-09-28 | — | — | CN | disclosed |
| CN-101732607-A | Method for detecting quality of huaqi Chinese medicinal preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-06-16 | — | — | CN | disclosed |
| CN-101637567-A | Rhizoma ligustici wallichii quality control method in Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-02-03 | — | — | CN | disclosed |
| CN-101637566-A | Salvia miltiorrhiza quality control method in Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL | 2010-02-03 | — | — | CN | disclosed |
| CN-101596274-A | The method of quality control of Fructus Schisandrae Chinensis in the YIXINSHU Chinese medicine preparation | GUIZHOU XINBANG PHARMACEUTICAL (CN) | 2009-12-09 | — | — | CN | disclosed |
| CN-101036748-A | Quality control method of the Yixinshu Chinese traditional medicine for supplementing qi and for promoting blood circulation by removing blood stasis | GUIZHOU XINBANG PHARMACEUTICAL (CN) | 2007-09-19 | — | — | CN | disclosed |
| CN-1834629-A | Kit for discriminating breewing vinegar and preparing vinegar | INST OF HYGIENICS & ENVIRONMEN (CN) | 2006-09-20 | — | — | CN | disclosed |
| CN-1621836-A | Quality controlling method for pulse restoring injection | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2005-06-01 | — | — | CN | disclosed |
| JP-H03246209-A | COSMETIC | NIPPON CREATE KK | 1991-11-01 | — | — | JP | disclosed |