Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795129 | 0.87 | GSR (0.45) | GSRBCHEALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL9501683 | 0.87 | GSR (0.45) | GSRBCHEALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL9128824 | 0.83 | GSR (0.41) | GSRBCHEALDH1A1MAPTTDP1 | |
| SCHEMBL9795186 | 0.82 | GSR (0.51) | GSRBCHEALDH1A1MAPTCA2 | |
| SCHEMBL9497885 | 0.81 | GSR (0.42) | GSRBCHEMAPTTDP1L3MBTL1 | |
| SCHEMBL9795375 | 0.81 | GSR (0.42) | GSRBCHEMAPTTDP1L3MBTL1 | |
| SCHEMBL9795291 | 0.78 | GSR (0.42) | GSRBCHEALDH1A1MAPTCA2 | |
| SCHEMBL9795344 | 0.78 | GSR (0.44) | GSRBCHEALDH1A1MAPTCA2 | |
| Fumaric Acid SCHEMBL9795206 | 0.77 | GSR (0.41) | GSRBCHEALDH1A1SMN1; SMN2CA2 | |
| SCHEMBL9019570 | 0.76 | GSR (0.51) | GSRBCHEALDH1A1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |