Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 5/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129731 | 0.89 | TBXA2R (0.67) | SGMS1TBXA2RMEN1KMT2APPARG | |
| SCHEMBL9127737 | 0.88 | F2 (0.62) | SGMS1TBXA2RTBXAS1PRMT1AKR1C3 | |
| SCHEMBL9127032 | 0.85 | TBXA2R (0.64) | SGMS1TBXA2RMEN1KMT2APPARG | |
| SCHEMBL9129164 | 0.81 | SGMS1 (0.55) | SGMS1TBXA2RMEN1KMT2ATBXAS1 | |
| SCHEMBL9129452 | 0.80 | MEN1 (0.58) | SGMS1TBXA2RMEN1KMT2APPARG | |
| SCHEMBL8840163 | 0.80 | TBXA2R (0.79) | SGMS1TBXA2RMEN1KMT2ATBXAS1 | |
| SCHEMBL9128346 | 0.79 | SGMS1 (0.57) | SGMS1TBXA2RMEN1KMT2ATBXAS1 | |
| SCHEMBL9128779 | 0.79 | F2 (0.51) | SGMS1TBXA2RMEN1KMT2AALDH1A1 | |
| SCHEMBL9510832 | 0.79 | TBXA2R (0.54) | SGMS1TBXA2RMEN1KMT2APPARG | |
| SCHEMBL9128700 | 0.79 | MEN1 (0.65) | SGMS1TBXA2RMEN1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |