Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127737 | 0.91 | F2 (0.62) | F2AKR1C3CYP2D6PLGSGMS1 | |
| SCHEMBL9129388 | 0.82 | TBXA2R (0.62) | AKR1C3L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9130159 | 0.82 | DRD4 (0.55) | F2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9128548 | 0.81 | ALDH1A1 (0.56) | F2AKR1C3L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9129003 | 0.79 | SGMS1 (0.57) | AKR1C3ALDH1A1MEN1KMT2ASGMS1 | |
| SCHEMBL9129268 | 0.78 | F2 (0.60) | F2AKR1C3ALDH1A1PLGSGMS1 | |
| SCHEMBL9129275 | 0.78 | F2 (0.60) | F2AKR1C3ALDH1A1PLGSGMS1 | |
| SCHEMBL3394469 | 0.77 | L3MBTL1 (0.68) | AKR1C3L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9129394 | 0.77 | SGMS1 (0.74) | L3MBTL1ALDH1A1KMT2ARAB9ASGMS1 | |
| SCHEMBL9850603 | 0.77 | SGMS1 (0.59) | F2AKR1C3PLGSGMS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |