Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986987 | 1.00 | CYP4F2 (0.46) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL8987098 | 1.00 | CYP4F2 (0.46) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL4650865 | 0.98 | CYP4F2 (0.43) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL4122676 | 0.92 | CYP4F2 (0.40) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL1661232 | 0.83 | DGAT1 (0.38) | CYP4F2CYP4A11TSHRDGAT1ELANE | |
| SCHEMBL23971207 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL14809987 | 0.82 | TSHR (0.52) | CYP4F2CYP4A11ACLYTSHRKMT2A | |
| SCHEMBL28738660 | 0.82 | TSHR (0.52) | CYP4F2CYP4A11ACLYTSHRKMT2A | |
| SCHEMBL23970490 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11ACLYACACBACACA | |
| SCHEMBL14891456 | 0.82 | TSHR (0.52) | CYP4F2CYP4A11ACLYTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468888-A | Lupane derivatives, their preparation and the pharmaceutical compositions which contain them | RHONE-POULENC RORER S.A. (FR) | 1995-11-21 | — | — | US | disclosed |