Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 6/20 | 0.53 |
| ▸ | HTR7 | P34969 | 6/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126892 | 0.91 | F2 (0.61) | F2PLGMEN1KMT2AHTR1A | |
| SCHEMBL9128289 | 0.88 | LSS (0.55) | MEN1KMT2AHTR1AHTR7TBXA2R | |
| SCHEMBL9127860 | 0.83 | MEN1 (0.58) | F2MEN1KMT2AHTR1AHTR7 | |
| SCHEMBL9126951 | 0.81 | F2 (0.69) | F2PLGMEN1KMT2ATBXA2R | |
| SCHEMBL10446945 | 0.81 | F2 (0.66) | F2PLGMEN1KMT2ATBXA2R | |
| SCHEMBL9129898 | 0.81 | F2 (0.68) | F2PLGMEN1KMT2ATBXA2R | |
| Hydrochloric Acid SCHEMBL9132077 | 0.80 | F2 (0.68) | F2PLGMEN1KMT2ATBXA2R | |
| SCHEMBL9128145 | 0.80 | F2 (0.68) | F2PLGMEN1KMT2ATBXA2R | |
| SCHEMBL9128510 | 0.79 | F2 (0.67) | F2PLGMEN1KMT2ATBXA2R | |
| SCHEMBL9127531 | 0.79 | LTA4H (0.59) | MEN1KMT2AHTR1AHTR7TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |