Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.40 |
| ▸ | GNG2 | P59768 | 1/20 | 0.38 |
| ▸ | GNB1 | P62873 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130024 | 0.86 | KDM4E (0.45) | GSK3BKMT2APTPN1GNG2GNB1 | |
| SCHEMBL11366826 | 0.81 | ALDH1A1 (0.45) | KMT2A | |
| SCHEMBL15927445 | 0.80 | GSK3B (0.46) | GSK3BPTPN1GNG2GNB1 | |
| SCHEMBL30967946 | 0.78 | KMT2A (0.40) | KMT2A | |
| SCHEMBL30437369 | 0.77 | KMT2A (0.47) | KMT2ABRD4 | |
| SCHEMBL1339915 | 0.77 | KMT2A (0.47) | KMT2ABRD4 | |
| SCHEMBL11361750 | 0.77 | ELANE (0.46) | KMT2AMEN1 | |
| SCHEMBL11370498 | 0.76 | KMT2A (0.41) | KMT2AF2F10CYP3A4 | |
| SCHEMBL5859196 | 0.75 | KMT2A (0.48) | KMT2AF2BRD4 | |
| SCHEMBL2464708 | 0.75 | KMT2A (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385931-A | Multistage formation of sulfonamides by reaction of esters and acyl halides, nitriding, reduction and sulfonylation to form cardiovascular compounds | PIERRE FABRE MEDICAMENT (FR) | 1995-01-31 | — | — | US | disclosed |