SCHEMBL9129456

SCHEMBL9129456

S=c1c2ccccc2sc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.68
ALDH1A1 P00352 6/20 0.46
MAPT P10636 4/20 0.46
HPGD P15428 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
LIMK1 P53667 2/20 0.42
IKBKB O14920 1/20 0.42
KDM4E B2RXH2 4/20 0.41
ALOX15 P16050 2/20 0.40
LOXL2 Q9Y4K0 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 1/20 0.39
PSMB8 P28062 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29008118 0.97 GPR3 (0.65) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL30167635 0.82 GPR3 (1.00) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL14659543 0.82 GPR3 (1.00) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL13294 0.82 GPR3 (1.00) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL1285223 0.82 KDM4E (0.64) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL28741339 0.80 GPR3 (0.45) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL28345479 0.80 GPR3 (0.82) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL3101427 0.79 GPR3 (0.93) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL10943387 0.79 GPR3 (0.93) GPR3ALDH1A1MAPTHPGDRAB9A
Dibenzothiophene SCHEMBL9934048 0.79 GPR3 (0.93) GPR3ALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520574-A1 Thioxanthone derivatives GREAT LAKES FINE CHEMICALS LIMITED (GB) 1992-12-30 EP claimed
JP-5208971-A None JP disclosed
CN-113784755-B Salts of isochroman-based compounds, crystalline forms thereof, methods of preparation, therapeutic uses and pharmaceutical compositions 赛诺维信制药公司 2024-05-10 CN disclosed
CN-112062730-B 4-oxo-3, 4-dihydro-1, 2, 3-benzotriazines as modulators of GPR139 武田药品工业株式会社 2023-09-29 CN disclosed
CN-112004811-B Compounds that modulate AMPA receptor function 加的夫大学学院咨询有限公司 2023-09-22 CN disclosed
CN-116456972-A Prolonged release pharmaceutical formulations 道格拉斯制药有限公司 2023-07-18 CN disclosed
CN-110678500-B Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2022-10-14 CN disclosed
CN-110678500-A Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2020-01-10 CN disclosed
US-9170495-B2 Phenol monomer, polymer for forming a resist underlayer film including same, and composition for a resist underlayer film including same DONGJIN SEMICHEM CO., LTD. (KR) 2015-10-27 US disclosed
US-9170495-B2 Phenol monomer, polymer for forming a resist underlayer film including same, and composition for a resist underlayer film including same DONGJIN SEMICHEM CO., LTD. (KR) 2015-10-27 US disclosed
US-20140319097-A1 PHENOL MONOMER, POLYMER FOR FORMING A RESIST UNDERLAYER FILM INCLUDING SAME, AND COMPOSITION FOR A RESIST UNDERLAYER FILM INCLUDING SAME DONGJIN SEMICHEM CO., LTD. (KR) 2014-10-30 US disclosed
US-20140319097-A1 PHENOL MONOMER, POLYMER FOR FORMING A RESIST UNDERLAYER FILM INCLUDING SAME, AND COMPOSITION FOR A RESIST UNDERLAYER FILM INCLUDING SAME DONGJIN SEMICHEM CO., LTD. (KR) 2014-10-30 US disclosed
US-5414092-A Photoinitiators INTERNATIONAL BIO-SYNTHETICS LIMITED (GB) 1995-05-09 US disclosed
JP-H05208971-A THIOXANTHONE DERIVATIVE INTERNATL BIO SYNTHETICS LTD 1993-08-20 JP disclosed
EP-0520574-A1 Thioxanthone derivatives GREAT LAKES FINE CHEMICALS LIMITED (GB) 1992-12-30 EP disclosed