Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.59 |
| ▸ | NOS1 | P29475 | 1/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.59 |
| ▸ | DHFR | P00374 | 4/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124919 | 0.83 | NOS3 (0.44) | NOS3NOS1NOS2GABRPGABRD | |
| SCHEMBL9127258 | 0.82 | NOS3 (0.42) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL21076465 | 0.81 | NOS3 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL24481591 | 0.78 | NOS3 (0.59) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL7203119 | 0.77 | NOS3 (0.63) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL7120097 | 0.77 | NOS3 (0.63) | NOS3NOS1NOS2DHFRSLC6A2 | |
| SCHEMBL17450397 | 0.74 | NOS3 (0.59) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL13547520 | 0.74 | NOS3 (0.59) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL8322579 | 0.74 | NOS3 (1.00) | NOS3NOS1NOS2DHFRGABRP | |
| SCHEMBL9133817 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399488-A | Kidneys | NITTO BOSEKI CO., LTD. (JP) | 1995-03-21 | — | — | US | disclosed |