Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657887 | 0.82 | MAPT (0.48) | MAPTL3MBTL1KMT2AALDH1A1KLK7 | |
| SCHEMBL1884728 | 0.77 | KMT2A (0.35) | KMT2AALDH1A1SMN1; SMN2MEN1UTS2R | |
| SCHEMBL1884773 | 0.77 | MAPT (0.40) | MAPTL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL1884726 | 0.77 | MAPT (0.40) | MAPTL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL9335595 | 0.77 | HPGD (0.67) | MAPTKMT2AALDH1A1HPGDNPC1 | |
| SCHEMBL2231578 | 0.75 | UTS2R (0.39) | KMT2AUTS2R | |
| SCHEMBL2231583 | 0.75 | KMT2A (0.41) | KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2231576 | 0.74 | GABBR2 (0.44) | MAPTKMT2ARAB9AMEN1UTS2R | |
| SCHEMBL637841 | 0.74 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL637840 | 0.74 | UTS2R (0.36) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401868-A | Sulfiding and esterification to form chemical intermediates | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUCTIONSAKTIESELSKAB) (DK) | 1995-03-28 | — | — | US | disclosed |
| EP-0541550-B1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE | LEO PHARM PROD LTD (DK) | 1994-09-07 | — | — | EP | disclosed |
| EP-0541550-A1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE. | LEO PHARM PROD LTD (DK) | 1993-05-19 | — | — | EP | disclosed |
| WO-1991010639-A1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1991-07-25 | — | — | WO | disclosed |