Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074396 | 0.80 | KCNN4 (0.48) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL26063349 | 0.77 | KCNN4 (0.64) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2488777 | 0.73 | KCNN4 (0.68) | KCNN4KIF11TSHRACHEL3MBTL1 | |
| SCHEMBL28244087 | 0.69 | ESR1 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL430195 | 0.69 | ESR1 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3114470 | 0.69 | HDAC3 (0.45) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1549012 | 0.69 | HDAC3 (0.45) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10918052 | 0.68 | KIF11 (0.31) | KIF11TSHRACHE | |
| SCHEMBL9632116 | 0.68 | TSHR (0.43) | KCNN4KIF11TSHRACHEMEN1 | |
| SCHEMBL2780246 | 0.66 | KCNN4 (0.46) | KCNN4KIF11TSHRACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455363-A | Having trityl as amide-protecting group for asparagine and glutamine; reduced side reaction | GOSTELI JACQUES (CH) | 1995-10-03 | — | — | US | disclosed |