Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | RXRB | P28702 | 1/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17157579 | 0.84 | RXRA (0.61) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL8829480 | 0.83 | NQO1 (0.56) | MAPTTDP1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29426410 | 0.82 | RXRA (0.66) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL9260410 | 0.82 | RXRA (0.66) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL1483077 | 0.81 | ABL1 (0.53) | BRD4CYP3A4 | |
| SCHEMBL18725084 | 0.81 | RXRA (0.62) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL410570 | 0.81 | KDM4E (0.57) | RXRARXRBBRD4BRD2CREBBP | |
| SCHEMBL30338775 | 0.81 | RXRA (0.70) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL203120 | 0.81 | RXRA (0.70) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL29012837 | 0.80 | RXRA (0.64) | RXRARXRBFGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444210-B1 | ARYLSTYRENE POLYMER AND COPOLYMER AND PROCESS FOR PREPARING THE SAME | IDEMITSU KOSAN CO (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5403908-A | Aryl styrene-based copolymer | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| EP-0444210-A1 | ARYLSTYRENE POLYMER AND COPOLYMER AND PROCESS FOR PREPARING THE SAME | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-09-04 | — | — | EP | disclosed |