Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130383 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9134274 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9134266 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9131692 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9130964 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9130971 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9131699 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9132199 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL9132204 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 | |
| SCHEMBL7022795 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPK1HPGDTHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399563-A | Sunscreen agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-03-21 | — | — | US | disclosed |