Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.79 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.71 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.71 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.71 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.71 |
| ▸ | ALB | P02768 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GLI1 | P08151 | 1/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.71 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.71 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129198 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9129077 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9134169 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9133467 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9129965 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9131314 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9131230 | 1.00 | RORC (0.79) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9131351 | 0.99 | RORC (0.81) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9131582 | 0.96 | RORC (0.74) | RORCEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL9131971 | 0.96 | RORC (0.74) | RORCEGLN2EGLN1EGLN3P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468888-A | Lupane derivatives, their preparation and the pharmaceutical compositions which contain them | RHONE-POULENC RORER S.A. (FR) | 1995-11-21 | — | — | US | disclosed |