Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130464 | 1.00 | MAOB (0.64) | MAOBSCN9AMAOAHRH3HRH1 | |
| SCHEMBL7389604 | 0.95 | MAOB (0.59) | MAOBSCN9AMAOAHRH3HRH1 | |
| SCHEMBL23440921 | 0.87 | MAOB (0.67) | MAOBSCN9AMAOAHRH3HRH1 | |
| SCHEMBL4456855 | 0.87 | MAOB (0.74) | MAOBSCN9AMAOAHRH3 | |
| SCHEMBL1070615 | 0.87 | MAOB (0.74) | MAOBSCN9AMAOAHRH3 | |
| SCHEMBL7403715 | 0.87 | MAOB (0.74) | MAOBSCN9AMAOAHRH3 | |
| SCHEMBL8806977 | 0.86 | LMNA (0.49) | MAOBSCN9AMAOAHRH3HRH1 | |
| SCHEMBL23440930 | 0.86 | MAOB (0.76) | MAOBSCN9AMAOAHRH3 | |
| SCHEMBL23440948 | 0.86 | MAOB (0.65) | MAOBSCN9AMAOAHRH3 | |
| SCHEMBL23440991 | 0.86 | MAOB (0.76) | MAOBSCN9AMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |