Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 8/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840163 | 0.89 | TBXA2R (0.79) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9127040 | 0.88 | TBXA2R (0.81) | SGMS1TBXA2RTBXAS1ALDH1A1HTT | |
| SCHEMBL23294744 | 0.88 | TBXA2R (0.73) | SGMS1TBXA2RTBXAS1ALDH1A1HTT | |
| SCHEMBL9127508 | 0.86 | F2 (0.68) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9127591 | 0.84 | SGMS1 (0.76) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9129860 | 0.84 | TSHR (0.65) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9127709 | 0.83 | MEN1 (0.70) | TBXA2RTBXAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL9126335 | 0.83 | TBXA2R (0.78) | TBXA2RMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL9128585 | 0.83 | SGMS1 (0.62) | SGMS1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL9301142 | 0.83 | SGMS1 (0.62) | SGMS1TBXA2RTBXAS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | claimed |
| US-5446065-A | Thromboxane antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0564499-B1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011234-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1992-07-09 | — | — | WO | disclosed |